DermaZinc™ Advanced Formula W/ Micronized Betamethasone Dipropionate USP Compounding Instructions:
Spray: Add 64mg of Micronized Betamethasone Dipropionate USP directly to a 4 oz. (120ml) bottle of DermaZinc™ Spray (wt = 100gm), estimated 6 months stability when compounded. Instruct patient to shake well before using & keep away from extreme heat.
Cream: Levigate 77mg of Micronized Betamethasone Dipropionate USP with a small amount of Glycerin or Mineral Oil and mix into a 4 oz. (120gm) jar of DermaZinc™ Cream, or add 6 cc of stock solution (see below) to 120 gm jar of DermaZinc™ Cream. Estimated 6 months stability when compounded.
Shampoo: Whisk 144mg of Micronized Betamethasone Dipropionate USP into a 8 oz. (240ml) bottle of DermaZinc™ Shampoo, or add 11cc of stock solution (see below) to 240ml bottle of DermaZinc™ Shampoo. Estimated 6 months stability when compounded. Instruct patient to shake well before each use.
Commonly asked questions:
What inert substance should be used when Pharmacist scale cannot weigh small quantities?
If your balance can not weigh small amounts, dissolve 640mg of Micronized Betamethasone Dipropionate USP into 50cc of 99% isopropyl alcohol 12.8mg stock solution =1cc. Add 5cc of this to 120cc DermaZinc™ Spray, or 6cc to DermaZinc™ Cream (120gm) or 11cc to DermaZinc™ Shampoo (240ml). A better way to treat the scalp is to use DermaZinc™ Shampoo in conjunction with DermaZinc™ w/ Betamethasone Dipropionate USP product using the dropper tip. The rational is that the Rx Shampoo is washed out quickly whereas you massage in the drops. Estimated stability once compounded is six months. Estimated stock solution stability is one year from date of compounding.
How come when I calculate the formula my answer is different?
Each gram of finished product contains 0.64mg Micronized Betamethasone Dipropionate USP is equivalent to 0.5mg of Micronized Betamethasone USP w/w.
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